产品货号：
Z13143
中文名称：
CHEK2抗体
英文名称：
Anti-CHEK2 Antibody (N-term)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CHEK2 Antibody (N-term) |
| 指标别名 | CDS1;CHEK2;Chk2;HuCds1;LFS2;PP1425;RAD53 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IF,FCM,IHC |
| 基因名称 | CHEK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This CHEK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-141 amino acids from the N-terminal region of human CHEK2. |
| 计算分子量 | 61kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | CHEK2 is a cell cycle checkpoint regulator and putative tumor suppressor.It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage.When activated,the encoded protein is known to inhibit CDC25C phosphatase,preventing entry into mitosis,and has been shown to stabilize the tumor suppressor protein p53,leading to cell cycle arrest in G1.In addition,this protein interacts with and phosphorylates BRCA1,allowing BRCA1 to restore survival after DNA damage.Mutations in this gene have been linked with Li-Fraumeni syndrome,a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. |
| Uniprot ID | O96017 |
相关搜索：CHEK2抗体，CHEK2(N-term)多抗，Anti-CHEK2 Antibody (N-term)